Stuart L Schreiber Selected Research

(4- (bis(4- chlorophenyl)methyl)- 1- piperazinyl)(5- methyl- 4- nitro- 1,2- oxazol- 3- yl)methanone

2/2012

Development of small-molecule probes that selectively kill cells induced to express mutant RAS.

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Stuart L Schreiber Research Topics

Disease

51	Neoplasms (Cancer) 01/2022 - 04/2003
7	Prion Diseases (Transmissible Spongiform Encephalopathies) 11/2020 - 01/2019
5	Malaria 12/2021 - 04/2015
4	Melanoma (Melanoma, Malignant) 01/2019 - 08/2008
4	Leukemia 09/2016 - 01/2010
4	Breast Neoplasms (Breast Cancer) 02/2016 - 06/2005
3	Communicable Diseases (Infectious Diseases) 01/2020 - 06/2007
3	Infections 01/2019 - 01/2007
3	Inflammation (Inflammations) 10/2017 - 12/2013
3	Multiple Myeloma 11/2016 - 06/2005
2	Chordoma 01/2021 - 01/2019
2	Tuberculosis (Tuberculoses) 01/2020 - 11/2007
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2019
2	Rhabdoid Tumor (Rhabdoid Tumors) 01/2020 - 01/2019
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2019 - 10/2014
2	Carcinoma (Carcinomatosis) 01/2017 - 10/2013
2	Type 2 Diabetes Mellitus (MODY) 01/2017 - 01/2011
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2016 - 09/2016
2	Parkinson Disease (Parkinson's Disease) 01/2016 - 06/2007
2	Ovarian Neoplasms (Ovarian Cancer) 07/2015 - 09/2011
2	Chagas Disease (American Trypanosomiasis) 02/2014 - 12/2011
2	Carcinogenesis 05/2013 - 03/2008
2	Huntington Disease (Huntington's Disease) 11/2007 - 06/2007
2	Hypersensitivity (Allergy) 05/2004 - 06/2003
1	Drug Hypersensitivity (Drug Allergy) 05/2022
1	Toxoplasmosis 01/2022
1	Pulmonary Hypertension 10/2021
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2020
1	Dementia (Dementias) 12/2019
1	Medullary Carcinoma 12/2019
1	Hypoxia (Hypoxemia) 01/2019
1	Liver Neoplasms (Liver Cancer) 01/2019
1	Persistent Infection 10/2018

Drug/Important Bio-Agent (IBA)

15	Pharmaceutical PreparationsIBA 10/2021 - 09/2009
7	Prion ProteinsIBA 11/2020 - 01/2019
7	Proteins (Proteins, Gene)FDA Link 01/2019 - 04/2002
6	Biomarkers (Surrogate Marker)IBA 01/2020 - 08/2013
5	LipidsIBA 01/2022 - 01/2017
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2014
4	Messenger RNA (mRNA)IBA 01/2019 - 09/2009
4	EnzymesIBA 04/2017 - 03/2008
4	piperlongumineIBA 09/2013 - 07/2011
4	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2013 - 03/2008
4	Histone Deacetylase InhibitorsIBA 01/2013 - 04/2003
4	Sirolimus (Rapamycin)FDA Link 11/2007 - 08/2003
3	PrionsIBA 01/2020 - 01/2019
3	Proteasome InhibitorsIBA 12/2019 - 06/2005
3	CytokinesIBA 10/2017 - 08/2014
3	Dihydroorotate DehydrogenaseIBA 04/2017 - 09/2016
3	Protein Kinases (Protein Kinase)IBA 08/2013 - 02/2002
3	Phosphotransferases (Kinase)IBA 12/2012 - 02/2012
2	AzetidinesIBA 12/2021 - 01/2020
2	Brachyury protein (Brachyury)IBA 01/2021 - 01/2019
2	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 10/2016
2	Antisense OligonucleotidesIBA 12/2019 - 01/2019
2	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2019 - 06/2005
2	6- (4- (diethylamino)- 3- nitrophenyl)- 5- methyl- 4,5- dihydropyridazin- 3(2H)- oneIBA 11/2019 - 02/2016
2	Lipid PeroxidesIBA 10/2018 - 01/2017
2	Interleukin-10 (Interleukin 10)IBA 10/2017 - 08/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 04/2002
2	Small Molecule LibrariesIBA 01/2016 - 05/2012
2	DNA (Deoxyribonucleic Acid)IBA 07/2015 - 09/2011
2	ChromatinIBA 01/2013 - 06/2011
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 12/2012 - 02/2012
2	Biological ProductsIBA 07/2011 - 11/2004
2	Neuregulin-1 (Neuregulin 1)IBA 07/2011 - 01/2010
2	Protein Isoforms (Isoforms)IBA 07/2010 - 03/2008
1	LactamsIBA 05/2022
1	HaptensIBA 05/2022
1	Immunoglobulin E (IgE)IBA 05/2022
1	azetidineIBA 01/2022
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022
1	IronIBA 01/2022
1	Phenylalanine (L-Phenylalanine)FDA Link 12/2021
1	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 12/2021
1	sulofenur (ISCU)IBA 10/2021
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2020
1	Tryptophan Synthase (Synthase, Tryptophan)IBA 01/2020
1	sulfolaneIBA 01/2020
1	Phospholipid Hydroperoxide Glutathione PeroxidaseIBA 01/2020
1	HomoharringtonineIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 12/2019
1	Ribonucleases (Ribonuclease)IBA 12/2019
1	Peptides (Polypeptides)IBA 12/2019
1	Ubiquitin-Conjugating EnzymesIBA 12/2019
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 11/2019
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2019
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2019
1	KynurenineIBA 01/2019
1	Asparaginase (Elspar)FDA Link 01/2019
1	Programmed Cell Death 1 ReceptorIBA 01/2019
1	GlycogenIBA 01/2019
1	Immune Checkpoint InhibitorsIBA 01/2019
1	NivolumabIBA 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 10/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2018
1	pyrimidineIBA 04/2017
1	Blood Glucose (Blood Sugar)IBA 01/2017

Therapy/Procedure

30	Therapeutics 10/2021 - 05/2003
1	Injections 01/2019